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Reply #18 zerozone's post.. b careful!!
There is a bogus report on the Internet purporting to be from the Journal of the American College of Toxicology (JACT). It is completely misleading and inaccurate. The original report from the Journal of the American College of Toxicology has been altered to create an inaccurate document. The erroneous report had been published at www.wwns.com/sanders/gh/lauryl.htm (no longer available).
The genuine report on SLS can be found in printed form in the JACT, Vol. 2 Number 7, 1983. The website of the American College of Toxicology, publishers of the JACT, is www.actox.org. It does NOT contain full texts of its reports.
This is an example of how information found on the Internet must be checked before using.
The Cosmetic, Toiletry, and Fragrance Association (CTFA) and the American Cancer Society have stated that the common belief that SLES is a carcinogen is an urban legend, a view confirmed by toxicology research by the OSHA, NTP, and IARC.[6] SLES and SLS, and subsequently the products containing them, have been found to contain parts-per-thousand to parts-per-million levels of 1,4-dioxane, with the recommendation that these levels be monitored.[7] The U.S. Environmental Protection Agency considers 1,4-dioxane to be a probable human carcinogen (having observed an increased incidence of cancer in controlled animal studies, but not in epidemiological studies of workers using the compound), and a known irritant (with a no-observed-adverse-effects level of 400 milligrams per cubic metre).[8] While the U.S. Food and Drug Administration encourages manufacturers to remove this contaminant, it is not currently required by federal law.[9]
Ref:
[6]Rumor: Sodium Lauryl Sulfate Causes Cancer. The Cosmetic, Toiletry, and Fragrance Association. 13, October 2000. Consumer Information
[7] Roderick E. Black, Fred J. Hurley, Donald C. Havery. Occurrence of 1,4-Dioxane in Cosmetic Raw Materials and Finished Cosmetic Products. Journal of AOAC International.2001 May;84(3):666-670. Abstract
[8]1,4-Dioxane (1,4-Diethyleneoxide). Hazard Summary. U.S. Environmental Protection Agency. Created in April 1992; Revised in January 2000. Fact Sheet
[9] FDA/CFSAN--Cosmetics Handbook Part 3: Cosmetic Product-Related Regulatory Requirements and Health Hazard Issues. Prohibited Ingredients and other Hazardous Substances: 9. Dioxane
sorry guys tak de masa i nak xplain.. but pls take note of these rumors!!! |
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Reply #19 wb_8w's post
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ala.. byk lagi syampo yg tak guna SLS ni. Kena rajin2 baca kat pelekat dia tu, kan ade written. be alert of what you put on your body, jgn main hentam je pakai tengok iklan gah kat media. |
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Reply #21 rebas's post
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Sodium laureth sulfate (SLES) mempunyai chemical properties yg berbeza dengan sodium lauryl sulfate (SLS). SLS banyak digunakan sebagai detergent untuk membersih lantai. Fakta yg sebenar SLS yg menimbulkan kesan buruk jika dibandingkan SLES. |
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Ethoxylation is the process that makes degreasing agents such as Sodium Lauryl Sulphate (SLS) less abrasive and gives them enhanced foaming properties. When SLS is ethoxylated, it forms Sodium Laureth Sulphate (SLES), a compound used in many shampoos, toothpastes, bath gels, bubble baths, and industrial degreasants. The problem is, the extremely harmful compound 1,4-dioxane may be created during the ethoxylation process, contaminating the product. 1,4-dioxane was one of the principal components of the chemical defoliant Agent Orange, used to great effect by the Americans during the Vietnam War to strip off the jungle canopy to reveal their enemy. 1,4-dioxane is a hormonal disrupter believed to be the chief agent implicated in the host of cancers suffered by Vietnam military personnel after the war. It is also an oestrogen mimic thought to increase the chances of breast cancer and endometrial cancer, stress related illnesses and lower sperm counts. |
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Research Article
Quantification of sodium lauryl sulfate penetration into the skin and underlying tissues after topical application - pharmacological and toxicological implications
Sunita Patil, Parminder Singh, Khaled Sarasour, Howard Maibach
Department of Dermatology, School of Medicine, Surge 110, University of California, San Francisco, CA 94143
From: Journal of Pharmaceutical Sciences
Vol 84, issue 10, Pages 1240-1244
Published Online: 17 Sep 2006
Copyright |
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SLS ,SLES do not cause cancer
Dear zerozone,
.. i nak explain yg .. so far tak de evidence yg SLS and SLES boleh menyebabkan cancer.. ada satu article dlm American journal of Toxicology yang you quote tu telah diubah dan disalah guna......(pls see..my reply).. yg may cause cancer in higher conc. is 1,4 dioxide.. (mind d spelling ..)
banyak benda kat dunia ni corrosive eg sabun basuh kain kat rumah... tapi corrosive property tak bermaksud sesuatu benda tu carcinogenic..
PS sorry x de masa nak explain earlier..
[ Last edited by rebas at 13-12-2007 12:46 PM ] |
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Titre du document / Document title
Protective role of ascorbic acid and α-tocopherol on arsenic-induced microsomal dysfunctions
Auteur(s) / Author(s)
RAMANATHAN K. (1) ; SHILA S. (1) ; KUMARAN S. (1) ; PANNEERSELVAM C. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Medical Biochemistry, Dr A.L. Mudaliar PG Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai-600 113, INDE
Coadministration of ascorbic acid and α-tocopherol to arsenic-exposed rats resulted in a reduction in the levels of lipid peroxidation, protein carbonyls and hydrogen peroxide and an elevation in the levels of reduced glutathione, ascorbic acid and α-tocopherol. Ascorbic acid and α-tocopherol treatment decreases the activity of haem oxygenase, whereas it increases the levels/ activity of cytochrome P450, cytochrome b[5] and NADPH-cytochrome P450 reductase in arsenic-intoxicated rats. The results of this study provide evidence that ascorbic acid and α-tocopherol supplementation can improve the arsenic-induced altered microsomal functions in liver and kidney.
Kajian yg dibuat diatas menunjukkan Vitamin C & E boleh mengurangkan kesan keracunan arsenik. Walaupun ada terdapat arsenic dalam seafood tetapi jumlahnya sangat sedikit dan tubuh boleh membuangnya dengan cara biasa. So kenyataan dalm info tak betul. |
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Originally posted by zerozone at 12-12-2007 09:26 PM 
Titre du document / Document title
Protective role of ascorbic acid and α-tocopherol on arsenic-induced microsomal dysfunctions
Auteur(s) / Author(s)
RAMANATHAN K. (1) ; SHILA S. (1) ; KU ...
Apa beza d-Alpha tocopherol dengan d/l -Alpha tocopherol (sintetik) berkaitan kekesanan antioksidan ? |
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Originally posted by Nazrulism at 12-12-2007 09:51 PM
Apa beza d-Alpha tocopherol dengan d/l -Alpha tocopherol (sintetik) berkaitan kekesanan antioksidan ?
alpha tocopherol mempunyai 3 methyl groups pada aromatic ring (pada posisi 5,7,8), dellta tocopherol hanya mempunyai 1 methyl group pada aromatic ring (pada posisi 8). Keupayaan antioksidan terletak pada free hydroxyl group dimana atom H dari tocopherol akan diderma kepada free radicals yg menyebabkan ia tak aktif. Alpha tocopherol yg mempunyai 3 methyl group lebih stabil dan lebih potensi dibandingkan delta tocopherol yg mempunyai 1 methyl group pada aromatic ring. |
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Reply #23 zerozone's post
Dear zerozone,
.. i nak explain yg .. so far tak de evidence yg SLS and SLES boleh menyebabkan cancer.. ada satu article dlm American journal of Toxicology yang you quote tu telah diubah dan disalah guna......(pls see..my reply).. yg may cause cancer in higher conc. is 1,4 dioxide.. (mind d spelling ..)
banyak benda kat dunia ni corrosive eg sabun basuh kain kat rumah,... tapi corrosive property TIDAK bermaksud sesuatu benda tu carcinogenic..
PS sorry x de masa nak explain earlier.. |
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Originally posted by zerozone at 13-12-2007 08:29 AM
alpha tocopherol mempunyai 3 methyl groups pada aromatic ring (pada posisi 5,7,8), dellta tocopherol hanya mempunyai 1 methyl group pada aromatic ring (pada posisi 8). Keupayaan antioksidan t ...
Adakah ini bermakna kita perlu mengambil 2 @ 3 kali ganda Sintetik Alpha tocopherol berbanding natural alpha tocopherol untuk mendapatkan kuantiti (IU) yang sama..? |
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Reply #30 rebas's post
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Mark Fearer in an article: Dangerous Beauty, says |
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Originally posted by Nazrulism at 13-12-2007 04:01 PM 
Adakah ini bermakna kita perlu mengambil 2 @ 3 kali ganda Sintetik Alpha tocopherol berbanding natural alpha tocopherol untuk mendapatkan kuantiti (IU) yang sama..?
Natural Vit E mempunyai biological activity 1.5 kali ganda berbanding synthetic Vit E. Juga natural Vit E lebih mudah diserap dan disimpan dlm liver berbanding natural. Jika kita mengambil synthetic Vit E beberapa kali ganda pun ianya tidak dapat menandingi keberkesanan natural Vit E. |
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Reply #32 zerozone's post
ok.. zerozone you guna shampoo apa? sabun apa? ... curious juga nak tahu.. since you are so careful about all this potential biohazard .... i believe companies yg guna SLS and SLES mesti monitor dioxane level kan.. untuk diluluskan dalam pasaran..... |
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Reply #35 rebas's post
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Saya tak guna shampoo, sabun susu kambing. Beberapa bulan yg lalu kita dengar berita bahawa USA mengharamkan ubat gigi colgate yg diimport dari China. Sebabnya China gunakan glycol instead of glycerine. Glycol ini juga sebagai penyumbang keracunan dioxane. Mengapa China tak banned penggunaan glycol dlm ubat gigi? Sebab glycol lebih murah dibandingkan glycerine. Dan sudah tentu ia boleh menjual barang dia dgn harga murah. Begitu juga dengan SLS & SLES...ia lebih murah. Apa yg kita nak tunjukkan disini ialah kemungkinan2 yg SLS & SLES ini boleh membawa mudarat kpd pengguna mengikut hasil2 kajian yg dilakukan. Dan orang2 yg menjalankan kajian tentang SLS & SLES ni pun takde kepentingan apa2...cuma nak menyedarkan pengguna bahawa sesetengah bahan kimia tu boleh mendatangkan bahaya jika digunakan dengan banyak dan dalam jangkamasa yg panjang. Dalam perubatan juga you pasti tahu mengapa pseudoephedrine baru sekarang diharamkan sedangkan bahan ni dah digunakan berpuluh tahun dalam ubat batok dan selsema. |
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CAP: Soft drinks may cause cell damage
PENANG: The Government has been urged to phase out the use of sodium benzoate as a preservative in soft drinks because research has shown that it can cause cell damage.
Consumers Association of Penang (CAP) president S.M. Mohd Idris said a recent research done by Professor Peter Piper from Sheffield University in England suggested that this common preservative could switch off vital parts of the DNA, causing serious cell damage in humans.
揙nce the cell is damaged, it might eventually lead to degenerative diseases such as Parkinson抯 disease, |
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Reply #36 zerozone's post
ooo my goodness... you mean you tak shampoo rambut..? hehehe.... ada jugak org Malaysia tak shampoo.. or you guna sabun kambing untuk shampoo rambut kut... hmmsmmnnnn...i wonder kesian your wife.. surely cosmetics and shampoos pun dia tak leh guna ye.. well up to u lah i suppose.. for me i like to have healthy, shiny , CLEAN hair.. yang kena shampoo and conditioned selalu..
oo ye zerozone... nak tanya.. ... Kalau nak accuse someone of murder.. mesti ada evidence and mangsa yg kena bunuh kan.. So kalau SLS and SLES contribute to cancer.. cancer bahagian mana ye.. Skin? Liver?(mcm association Hepatitis B), tulang? gigi? gusi?
kalau ikut logiknya kan.. SLS and SLES banyak kena scalp/ skin/ and diabsorb oleh kulit kan.. so far tak de lak i tahu ada cancer kulit sbb ni?? |
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Reply #38 rebas's post
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U tak baca post saya sebelom ni betul2. SLS dan SLES mempunyai estrogen like effect Dan mereka membuat hypothesis bahawa SLS dan SLES boleh menyebabkan breast cancer. |
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tq for info yg berguna ni.......ada yg betul dan boleh dipercayailah |
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Post time 11-12-2007 06:31 PM
tq Zerozone.. betullah selama ni kita hanya 'memperkayakan urin' dengan mengambil vitamin sintetik... 
