Mechanism β how it works?
Cialis is PDE 5 inhibitor and it belongs to PDE5 inhibitor class of drugs. It works in the similar way as the Viagra and levitra. The cGMP is formed in the smooth muscles of the arterial blood vessels of the penile tissue on sexual excitation. The penis is inflated like a balloon with excess of blood flowing into widened arteries due to this chemical messenger. The enzyme called PDE5 is responsible for the getting the penis back to the flaccid state which done by removing the cGMP from the smooth muscles of the arterial walls.
This enzyme is stopped to act by the drug with its main ingredient tadalafil. As a result, the penile tissue can stay erect for loner time and this ingredient can stay in action for as long as 36 hours but this doesn't mean that the penis will remain erect for 36 hours. One gets erection only after sexual excitation as it happens normally. If there will be no cGMP there will be no PDE5 and in turn there will be no erection! Hence, sexual excitation remains to be the factor for causing an erection and cialis works by helping the individual to get fuller erection.
It has nothing to do with the time of erection and ejaculation. In some studies it's known to improve the libido and increase the time of sexual act but there's no direct mechanism proving its action on sexual drive and time of ejaculation.
Thus, it's not a medicine for premature ejaculation, lesser or higher sexual drive but it's used for the treatment of inability to get fuller erections in case there are no or partial erections. In a study it was proved the women are more satisfied with harder penis and feel better orgasms, thus, erections play a key role in satisfying your spouse or your partner. Cialis is a boon for men with ED and it's the best cure that works for 36 hours at stretch so that you never need to repeat a pill like Viagra.
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